R. M. OBALLA : rechercher sur Z-Library

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1

Governing climate change for a just city: challenges and lessons from Maputo, Mozambique

Castán Broto, Vanesa, Oballa, Bridget, Junior, Paulo

Journal:

Local Environment

Année:

2013

Langue:

english

Fichier:

PDF, 372 KB

english, 2013

2

Technology for Producing Petrochemical Feedstock from Heavy Aromatic Oil Fractions

Simanzhenkov, Vasily, Oballa, Michael C., Kim, Grace

Journal:

Industrial & Engineering Chemistry Research

Année:

2010

Langue:

english

Fichier:

PDF, 648 KB

english, 2010

3

Coke formation in steam crackers for ethylene production

Haiyong Cai, Andrzej Krzywicki, Michael C Oballa

Journal:

Chemical Engineering and Processing: Process Intensification

Année:

2002

Langue:

english

Fichier:

PDF, 944 KB

english, 2002

4

Cathepsin K inhibitors increase distal femoral bone mineral density in rapidly growing rabbits

Pennypacker, Brenda L, Oballa, Renata M, Levesque, Sonia, Kimmel, Donald B, Duong, Le T

Journal:

BMC Musculoskeletal Disorders

Année:

2013

Langue:

english

Fichier:

PDF, 859 KB

english, 2013

5

Practical Asymmetric Synthesis of a Potent Cathepsin K Inhibitor. Efficient Palladium Removal Following Suzuki Coupling

Chen, Cheng-yi, Dagneau, Philippe, Grabowski, Edward J. J., Oballa, Renata, O'Shea, Paul, Prasit, Peppi, Robichaud, Joël, Tillyer, Rich, Wang, Xin

Journal:

Journal of Organic Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 99 KB

english, 2003

6

Adaptive-Implicit Method in Thermal Simulation (includes associated papers 23528 and 23571 )

Oballa, Viera, Coombe, Dennis A., Buchanan, W. Lloyd

Journal:

SPE Reservoir Engineering

Année:

1990

Langue:

english

Fichier:

PDF, 949 KB

english, 1990

7

Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1

Ian Paterson, David Y.-K. Chen, Mark J. Coster, Jose L. Aceña, Jordi Bach, Karl R. Gibson, Linda E. Keown, Renata M. Oballa, Thomas Trieselmann, Debra J. Wallace, Andrew P. Hodgson, Roger D. Norcross

Journal:

Angewandte Chemie

Année:

2001

Langue:

english

Fichier:

PDF, 143 KB

english, 2001

8

Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1

Ian Paterson, David Y.-K. Chen, Mark J. Coster, Jose L. Aceña, Jordi Bach, Karl R. Gibson, Linda E. Keown, Renata M. Oballa, Thomas Trieselmann, Debra J. Wallace, Andrew P. Hodgson, Roger D. Norcross

Journal:

Angewandte Chemie International Edition

Année:

2001

Langue:

english

Fichier:

PDF, 143 KB

english, 2001

9

ChemInform Abstract: Remote, 1,5-anti Stereoinduction in the Boron-Mediated Aldol Reactions of β-Oxygenated Methyl Ketones.

I. PATERSON, K. R. GIBSON, R. M. OBALLA

Journal:

Année:

1997

Fichier:

PDF, 34 KB

1997

10

ChemInform Abstract: Studies in Marine Macrolide Synthesis: Stereocontrolled Synthesis of the AB-Spiroacetal Subunit of Spongistatin 1 (Altohyrtin A).

I. PATERSON, R. M. OBALLA, R. D. NORCROSS

Journal:

Année:

1997

Fichier:

PDF, 28 KB

1997

11

ChemInform Abstract: Concise Total Syntheses of the Sesquiterpenoids (-)-Homalomenol A and ( -)-Homalomenol B.

E. PIERS, R. M. OBALLA

Journal:

Année:

1997

Fichier:

PDF, 30 KB

1997

12

ChemInform Abstract: Studies in Marine Macrolide Synthesis: Synthesis of the C1—C15 Subunit of Spongistatin 1 (Altohyrtin A) and 15,16-anti Aldol Coupling Reactions.

I. PATERSON, R. M. OBALLA

Journal:

Année:

1998

Fichier:

PDF, 33 KB

1998

13

ChemInform Abstract: Studies in Marine Macrolide Synthesis: Synthesis of a Fully Functionalized C1—C28 Subunit of Spongistatin 1 (Altohyrtin A).

I. PATERSON, D. J. WALLACE, R. M. OBALLA

Journal:

Année:

1999

Fichier:

PDF, 32 KB

1999

14

ChemInform Abstract: Synthesis of Cytotoxic Marine Macrolides: An Aldol-Based Approach to Spongistatin 1 (Altohyrtin A)

Ian Paterson, Karl R. Gibson, Linda E. Keown, Roger D. Norcross, Renata M. Oballa, Debra J. Wallace

Journal:

Année:

2000

Fichier:

PDF, 25 KB

2000

15

ChemInform Abstract: Novel, Nonpeptidic Cyanamides as Potent and Reversible Inhibitors of Human Cathepsins K and L.

Jean-Pierre Falgueyret, Renata M. Oballa, Osamu Okamoto, Gregg Wesolowski, Yves Aubin, Robert M. Rydzewski, Peppi Prasit, Denis Riendeau, Sevgi B. Rodan, M. David Percival

Journal:

Année:

2001

Fichier:

PDF, 28 KB

2001

16

Rational Design of Potent and Selective NH-Linked Aryl/Heteroaryl Cathepsin K Inhibitors.

Joel Robichaud, Christopher Bayly, Renata Oballa, Peppi Prasit, Christophe Mellon, Jean-Pierre Falgueyret, M. David Percival, Gregg Wesolowki, Sevgi B. Rodan

Journal:

Année:

2004

Fichier:

PDF, 10 KB

2004

17

Total Syntheses of the Sesquiterpenoids (+)-trans-Dracunculifoliol (I) and (+)-4-Hydroxyoppositan-7-one (II).

Renata M. Oballa, Rebekah Carson, Susan Lait, Jay A. Cadieux, Joel Robichaud

Journal:

Année:

2005

Fichier:

PDF, 11 KB

2005

18

Iterative annulations leading to functionalized tricyclo-[6.4.0.01,5]dodecanes and tricyclo[5.3.2.04,11]dodecanes

Edward Piers, Renata M Oballa

Journal:

Tetrahedron Letters

Année:

1995

Langue:

english

Fichier:

PDF, 223 KB

english, 1995

19

Remote, 1,5-anti stereoinduction in the boron-mediated aldol reactions of β-oxygenated methyl ketones

Ian Paterson, Karl R. Gibson, Renata M. Oballa

Journal:

Tetrahedron Letters

Année:

1996

Langue:

english

Fichier:

PDF, 247 KB

english, 1996

20

Studies in marine macrolide synthesis: Stereocontrolled synthesis of the AB-spiroacetal subunit of spongistatin 1 (altohyrtin A)

Ian Paterson, Renata M. Oballa, Roger D. Norcross

Journal:

Tetrahedron Letters

Année:

1996

Langue:

english

Fichier:

PDF, 247 KB

english, 1996

21

Rational design of potent and selective NH-linked aryl/heteroaryl cathepsin K inhibitors

Joël Robichaud, Christopher Bayly, Renata Oballa, Peppi Prasit, Christophe Mellon, Jean-Pierre Falgueyret, M David Percival, Gregg Wesolowski, Sevgi B Rodan

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 356 KB

english, 2004

22

A generally applicable method for assessing the electrophilicity and reactivity of diverse nitrile-containing compounds

Renata M. Oballa, Jean-François Truchon, Christopher I. Bayly, Nathalie Chauret, Stephen Day, Sheldon Crane, Carl Berthelette

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 263 KB

english, 2007

23

β-Substituted cyclohexanecarboxamide cathepsin K inhibitors: Modification of the 1,2-disubstituted aromatic core

Joël Robichaud, Christopher I. Bayly, W. Cameron Black, Sylvie Desmarais, Serge Léger, Frédéric Massé, Daniel J. McKay, Renata M. Oballa, Julie Pâquet, M. David Percival, Jean-François Truchon, Gregg

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 330 KB

english, 2007

24

Investigation of ketone warheads as alternatives to the nitrile for preparation of potent and selective cathepsin K inhibitors

Michael J. Boyd, Sheldon N. Crane, Joël Robichaud, John Scheigetz, W. Cameron Black, Nathalie Chauret, Qingping Wang, Frédéric Massé, Renata M. Oballa

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 163 KB

english, 2009

25

SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors

Yeeman K. Ramtohul, Cameron Black, Chi-Chung Chan, Sheldon Crane, Jocelyne Guay, Sébastien Guiral, Zheng Huang, Renata Oballa, Li-Jing Xu, Lei Zhang, Chun Sing Li

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2010

26

2-Aryl benzimidazoles: Human SCD1-specific stearoyl coenzyme-A desaturase inhibitors

David A. Powell, Yeeman Ramtohul, Marie-Eve Lebrun, Renata Oballa, Sathesh Bhat, Jean-Pierre Falgueyret, Sebastien Guiral, Zheng Huang, Kathryn Skorey, Paul Tawa, Lei Zhang

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 434 KB

english, 2010

27

Total syntheses of the sesquiterpenoids (+)-trans-dracunculifoliol and (+)-4-hydroxyoppositan-7-one

Renata M. Oballa, Rebekah Carson, Susan Lait, Jay A. Cadieux, Joël Robichaud

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 223 KB

english, 2005

28

Studies in marine macrolide synthesis: Synthesis of the C1C15 subunit of spongistatin 1 (altohyrtin A) and 15,16-anti aldol coupling reactions

Ian Paterson, Renata M. Oballa

Journal:

Tetrahedron Letters

Année:

1997

Langue:

english

Fichier:

PDF, 260 KB

english, 1997

29

A strategy for identification of drug metabolites from dried blood spots using triple-quadrupole/linear ion trap hybrid mass spectrometry

Timo Mauriala, Nathalie Chauret, Renata Oballa, Deborah A. Nicoll-Griffith, Kevin P. Bateman

Journal:

Rapid Communications in Mass Spectrometry

Année:

2005

Langue:

english

Fichier:

PDF, 257 KB

english, 2005

30

MSE with mass defect filtering for in vitro and in vivo metabolite identification

Kevin P. Bateman, Jose Castro-Perez, Mark Wrona, John P. Shockcor, Kate Yu, Renata Oballa, Deborah A. Nicoll-Griffith

Journal:

Rapid Communications in Mass Spectrometry

Année:

2007

Langue:

english

Fichier:

PDF, 253 KB

english, 2007

31

Oxidation Behavior of Ni–Cr–Fe-Based Alloys: Effect of Alloy Microstructure and Silicon Content

Yingcai Liu, Weifeng Wei, Les Benum, Mike Oballa, Mike Gyorffy, Weixing Chen

Journal:

Oxidation of Metals

Année:

2010

Langue:

english

Fichier:

PDF, 624 KB

english, 2010

32

Studies in marine macrolide synthesis: Synthesis of a fully functionalised C1C28 subunit of spongistatin 1 (altohyrtin A)

Ian Paterson, Debra J. Wallace, Renata M. Oballa

Journal:

Tetrahedron Letters

Année:

1998

Langue:

english

Fichier:

PDF, 257 KB

english, 1998

33

Peptidic 1-cyanopyrrolidines: synthesis and SAR of a series of potent, selective cathepsin inhibitors

Robert M Rydzewski, Clifford Bryant, Renata Oballa, Gregg Wesolowski, Sevgi B Rodan, Kathryn E Bass, Darren H Wong

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 180 KB

english, 2002

34

Effect of pore size on bitumen hydrocracking over Al2O3-AlPO4 supported Ni-Mo catalysts

Kevin J. Smith, Leszek Lewkowicz, Mike C. Oballa, Andrzej Krzywicki

Journal:

The Canadian Journal of Chemical Engineering

Année:

1994

Langue:

english

Fichier:

PDF, 753 KB

english, 1994

35

Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors

Jean-Philippe Leclerc, Jean-Pierre Falgueyret, Mélina Girardin, Jocelyne Guay, Sébastien Guiral, Zheng Huang, Chun Sing Li, Renata Oballa, Yeeman K. Ramtohul, Kathryn Skorey, Paul Tawa, Hao Wang, Lei

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 903 KB

english, 2011

36

Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: From systemic to liver-targeting inhibitors

Yeeman K. Ramtohul, David Powell, Jean-Philippe Leclerc, Serge Leger, Renata Oballa, Cameron Black, Elise Isabel, Chun Sing Li, Sheldon Crane, Joel Robichaud, Jocelyne Guay, Sébastien Guiral, Lei Zhan

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2011

37

Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker series

Nicolas Lachance, Sébastien Guiral, Zheng Huang, Jean-Philippe Leclerc, Chun Sing Li, Renata M. Oballa, Yeeman K. Ramtohul, Hao Wang, Jin Wu, Lei Zhang

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 498 KB

english, 2012

38

Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series

Nicolas Lachance, Yves Gareau, Sébastien Guiral, Zheng Huang, Elise Isabel, Jean-Philippe Leclerc, Serge Léger, Evelyn Martins, Christian Nadeau, Renata M. Oballa, Stéphane G. Ouellet, David A. Powell

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 881 KB

english, 2012

39

2-D systolic arrays for realization of 2-D convolution

Kwan, H.-K., Okullo-Oballa, T.S.

Journal:

IEEE Transactions on Circuits and Systems

Année:

1990

Langue:

english

Fichier:

PDF, 565 KB

english, 1990

40

Lysosomotropism of Basic Cathepsin K Inhibitors Contributes to Increased Cellular Potencies against Off-Target Cathepsins and Reduced Functional Selectivity

Lamontagne, Sonia, Massé, Frederic, Riendeau, Denis, Toulmond, Sylvie, Falgueyret, Jean-Pierre, Desmarais, Sylvie, Oballa, Renata, Black, W. Cameron, Cromlish, Wanda, Khougaz, Karine

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 353 KB

english, 2005

41

Carburization behaviour of Mn–Cr–O spinel in high temperature hydrocarbon cracking environment

Hao Li, Yanjun Zheng, Leslie W. Benum, Mike Oballa, Weixing Chen

Journal:

Corrosion Science

Année:

2009

Langue:

english

Fichier:

PDF, 712 KB

english, 2009

42

Polyembryony in Acacia karroo Hayne: insights from isozyme analysis

Phanuel O. Oballa

Journal:

African Journal of Ecology

Année:

1996

Langue:

english

Fichier:

PDF, 254 KB

english, 1996

43

The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the AB-spiroacetal segment

Paterson, Ian, Coster, Mark J., Chen, David Y.-K., Oballa, Renata M., Wallace, Debra J., Norcross, Roger D.

Journal:

Organic & Biomolecular Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 347 KB

english, 2005

44

Development of a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor (MK-8245) to Establish a Therapeutic Window for the Treatment of Diabetes and Dyslipidemia

Oballa, Renata M., Belair, Liette, Black, W. Cameron, Bleasby, Kelly, Chan, Chi Chung, Desroches, Carole, Du, Xiaobing, Gordon, Robert, Guay, Jocelyne, Guiral, Sebastien, Hafey, Michael J., Hamelin, E

Journal:

Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.27 MB

english, 2011

45

A Novel Class of Nonpeptidic Biaryl Inhibitors of Human Cathepsin K

Robichaud, Joël, Oballa, Renata, Prasit, Peppi, Falgueyret, Jean-Pierre, Percival, M. David, Wesolowski, Gregg, Rodan, Sevgi B., Kimmel, Donald, Johnson, Colena, Bryant, Cliff, Venkatraman, Shankar, S

Journal:

Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 521 KB

english, 2003

46

Novel, Nonpeptidic Cyanamides as Potent and Reversible Inhibitors of Human Cathepsins K and L

Falgueyret, Jean-Pierre, Oballa, Renata M., Okamoto, Osamu, Wesolowski, Gregg, Aubin, Yves, Rydzewski, Robert M., Prasit, Peppi, Riendeau, Denis, Rodan, Sevgi B., Percival, M. David

Journal:

Journal of Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 197 KB

english, 2001

47

Concise Total Syntheses of the Sesquiterpenoids (−)-Homalomenol A and (−)-Homalomenol B

Piers, Edward, Oballa, Renata M.

Journal:

Journal of Organic Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 474 KB

english, 1996

48

The discovery of benzenesulfonamide-based potent and selective inhibitors of voltage-gated sodium channel Nav1.7

Sun, Shaoyi, Jia, Qi, Zenova, Alla Y., Chafeev, Mikhail, Zhang, Zaihui, Lin, Sophia, Kwan, Rainbow, Grimwood, Mike E., Chowdhury, Sultan, Young, Clint, Cohen, Charles J., Oballa, Renata M.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 314 KB

english, 2014

49

Identification of a Nonbasic, Nitrile-Containing Cathepsin K Inhibitor (MK-1256) that is Efficacious in a Monkey Model of Osteoporosis

Robichaud, Jöel, Black, W. Cameron, Thérien, Michel, Paquet, Julie, Oballa, Renata M., Bayly, Christopher I., McKay, Daniel J., Wang, Qingping, Isabel, Elise, Léger, Serge, Mellon, Christophe, Kimm

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 511 KB

english, 2008

50

β-Substituted Cyclohexanecarboxamide: A Nonpeptidic Framework for the Design of Potent Inhibitors of Cathepsin K

Crane, Sheldon N., Black, W. Cameron, Palmer, James T., Davis, Dana E., Setti, Eduardo, Robichaud, Joel, Paquet, Julie, Oballa, Renata M., Bayly, Christopher I., McKay, Daniel J., Somoza, John R., Cha

Journal:

Journal of Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 452 KB

english, 2006